Djarum Black cigarettes sold in Europe, South Africa and South American countries have 10–12 mg tar and 1 mg nicotine, as indicated on the pack. This level of tar and nicotine is comparable to the majority of other regular or "full-flavor" cigarettes available.
However, Djarum Black cigarettes produced for consumption in Indonesia contain a significantly higher quantity of tar and nicotine, 25 mg and 1.6 mg respectively.
In Canada, Djarum Black cigarettes are listed as containing 44.2–86 mg of tar and 1.73–3.24 mg of nicotine, a significant amount more than most other cigarettes.
The venous plasma nicotine and carbon monoxide levels from 10 smokers were tested after smoking kreteks and were found to be similar to non-clove brands of cigarettes, such as Marlboro.
Rats were given equal inhalation doses of conventional tobacco cigarettes and kreteks over a short period. Those that had inhaled kreteks did not appear to show worse health effects compared to those that had inhaled conventional cigarettes. The study was repeated with a 14-day exposure and kreteks again did not produce worse health effects than conventional cigarettes.